Microarray Publications Database
Supplementary Data Table 3
Genes identified in MCF-7 cells by 2-way ANOVA as being significantly (p<0.05) affected by BaP concentration and exposure time.
Concentration down-regulated genes
IMAGE Clone ID | Gene Symbol | Genbank | Description | |
---|---|---|---|---|
173784 | TMSB4X | BM994376 | Thymosin, beta 4, X-linked | |
364975 | LCHN | AF136629 | LCHN protein | |
742596 | SYTL5 | BX647688 | Synaptotagmin-like 5 | |
2346678 | KIAA1324 | AB037745 | Maba1 | |
731750 | TAF6L | BC008785 | TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa | |
214006 | ||||
53243 | ASNS | NM_133436 | Asparagine synthetase | |
246377 | RHOBTB3 | NM_014899 | Rho-related BTB domain containing 3 | |
296479 | SULT1C1 | NM_176825 | Sulfotransferase family, cytosolic, 1C, member 1 | |
33386 | ||||
195052 | ||||
122293 | AA704763 | Transcribed locus | ||
128784 | KIAA0182 | NM_014615 | KIAA0182 protein | |
289505 | LOC201895 | BC047541 | Homo sapiens, clone IMAGE:5271877, mRNA | |
21892 | IARS | NM_013417 | Isoleucine-tRNA synthetase | |
486591 | SEMA3C | NM_006379 | Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | |
41922 | TARS | NM_152295 | Threonyl-tRNA synthetase | |
755046 | ||||
25465 | CSMD3 | NM_198123 | CUB and Sushi multiple domains 3 | |
186337 | FLJ13710 | BX641106 | Hypothetical protein FLJ13710 | |
729959 | KIAA1324 | AB037745 | Maba1 | |
200862 | CAV1 | NM_001753 | Caveolin 1, caveolae protein, 22kDa | |
758467 | NR2F2 | BC042897 | Nuclear receptor subfamily 2, group F, member 2 | |
280758 | TMSB4Y | NM_004202 | Thymosin, beta 4, Y-linked | |
51583 | SHMT2 | AK055053 | Serine hydroxymethyltransferase 2 (mitochondrial) | |
38154 | SEC8L1 | AL389977 | SEC8-like 1 (S. cerevisiae) | |
471254 | PDXK | NM_003681 | Pyridoxal (pyridoxine, vitamin B6) kinase | |
233279 | SCD | NM_005063 | Stearoyl-CoA desaturase (delta-9-desaturase) | |
197558 | LARGE | AJ007583 | Like-glycosyltransferase | |
760230 | AGR2 | BM924878 | Anterior gradient 2 homolog (Xenopus laevis) | |
810829 | PRSS23 | AL832007 | Transcribed locus, moderately similar to NP_955751.1 potassium channel regulator [Homo sapiens] | |
42800 | AI912163 | Transcribed locus | ||
291958 | KLF10 | S81439 | TGFB inducible early growth response | |
1184257 | LMNB1 | BC052951 | Lamin B1 | |
755474 | IARS | NM_013417 | Isoleucine-tRNA synthetase | |
214006 | ||||
221808 | NAP1L4 | AK095320 | Nucleosome assembly protein 1-like 4 | |
45542 | IGFBP5 | NM_000599 | Insulin-like growth factor binding protein 5 | |
486591 | SEMA3C | NM_006379 | Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | |
726791 | ||||
547247 | STC1 | NM_003155 | Stanniocalcin 1 | |
131867 | NET1 | BX537509 | Neuroepithelial cell transforming gene 1 | |
26617 | ALCAM | AL833702 | Activated leukocyte cell adhesion molecule |
Concentration up-regulated genes
IMAGE Clone ID | Gene Symbol | Genbank | Description |
---|---|---|---|
128041 | WDR40A | NM_015397 | WD repeat domain 40A |
2303100 | OLFM3 | NM_058170 | |
731081 | NALP4 | AF479747 | NACHT, leucine rich repeat and PYD containing 4 |
273392 | PIGF | BM558246 | Phosphatidylinositol glycan, class F |
239754 | SLC7A5 | AF104032 | Solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 |
297832 | |||
1584811 | ZSWIM5 | XM_046581 | Zinc finger, SWIM domain containing 5 |
233273 | STOM | NM_004099 | Stomatin |
201064 | USP34 | AB011142 | Ubiquitin specific protease 34 |
48518 | ABCA5 | NM_018672 | ATP-binding cassette, sub-family A (ABC1), member 5 |
294510 | CEP192 | NM_018069 | Centrosomal protein 192 kDa |
144000 | BZW1 | AL833518 | Basic leucine zipper and W2 domains 1 |
148297 | FBXO22 | NM_147188 | F-box protein 22 |
823688 | MAN1A1 | AK025599 | Mannosidase, alpha, class 1A, member 1 |
137201 | |||
263087 | CRY1 | AK125915 | Cryptochrome 1 (photolyase-like) |
760246 | BLOC1S2 | NM_001001342 | Biogenesis of lysosome-related organelles complex-1, subunit 2 |
150728 | TRIM16 | BX537711 | Tripartite motif-containing 16 |
381786 | MAK | NM_005906 | Male germ cell-associated kinase |
35516 | CCNG1 | NM_004060 | Cyclin G1 |
111753 | SIAT4A | BX537506 | Sialyltransferase 4A (beta-galactoside alpha-2,3-sialyltransferase) |
263446 | IDH1 | AF020038 | Isocitrate dehydrogenase 1 (NADP+), soluble |
166273 | CDKN1A | NM_078467 | Cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
324356 | NQO1 | NM_000903 | NAD(P)H dehydrogenase, quinone 1 |
268878 | CYP1B1 | NM_000104 | Cytochrome P450, family 1, subfamily B, polypeptide 1 |
205819 | CPM | NM_001874 | Carboxypeptidase M |
283648 | BM725828 | Transcribed locus | |
140997 | GDF15 | BQ883534 | Growth differentiation factor 15 |
782760 | CYP1B1 | NM_000104 | Cytochrome P450, family 1, subfamily B, polypeptide 1 |
768443 | MGST1 | AK123482 | Microsomal glutathione S-transferase 1 |
810724 | IER3 | BM994398 | Immediate early response 3 |
770704 | NCL | AK128584 | Nucleolin |
856454 | SLC3A2 | AK025584 | Solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 |
Time down-regulated genes
IMAGE Clone ID | Gene Symbol | Genbank | Description |
---|---|---|---|
471254 | PDXK | NM_003681 | Pyridoxal (pyridoxine, vitamin B6) kinase |
25398 | UNC84A | BX640866 | Unc-84 homolog A (C. elegans) |
233279 | SCD | NM_005063 | Stearoyl-CoA desaturase (delta-9-desaturase) |
128784 | KIAA0182 | NM_014615 | KIAA0182 protein |
756191 | SLC25A25 | AB067483 | Solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 |
1674713 | FLJ20032 | NM_017628 | Hypothetical protein FLJ20032 |
1187828 | MSMB | AK092543 | Microseminoprotein, beta- |
259060 | SIPA1 | AB005666 | Signal-induced proliferation-associated gene 1 |
273198 | RHOBTB3 | NM_014899 | Rho-related BTB domain containing 3 |
268927 | CCND1 | NM_053056 | Cyclin D1 (PRAD1: parathyroid adenomatosis 1) |
148379 | IGF1R | BX640783 | Transcribed locus, moderately similar to XP_375099.1 hypothetical protein LOC283585 [Homo sapiens] |
758467 | NR2F2 | BC042897 | Nuclear receptor subfamily 2, group F, member 2 |
25465 | CSMD3 | NM_198123 | CUB and Sushi multiple domains 3 |
289505 | LOC201895 | BC047541 | Homo sapiens, clone IMAGE:5271877, mRNA |
268891 | HIST1H3D | BQ051491 | Histone 1, H3d |
197558 | LARGE | AJ007583 | Like-glycosyltransferase |
755046 | |||
49731 | NEBL | Y16241 | Nebulette |
760061 | BX089736 | Transcribed locus | |
135500 | SLC7A2 | AL832016 | Solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 |
38154 | SEC8L1 | AL389977 | SEC8-like 1 (S. cerevisiae) |
810829 | PRSS23 | AL832007 | Transcribed locus, moderately similar to NP_955751.1 potassium channel regulator [Homo sapiens] |
129467 | HIST1H2BJ | BF983642 | Histone 1, H2bj |
1842170 | HIST1H4B | BX102654 | Histone 1, H4b |
186337 | FLJ13710 | BX641106 | Hypothetical protein FLJ13710 |
166966 | SLC39A6 | NM_012319 | Solute carrier family 39 (zinc transporter), member 6 |
296479 | SULT1C1 | NM_176825 | Sulfotransferase family, cytosolic, 1C, member 1 |
25304 | CUTL1 | NM_181552 | Cut-like 1, CCAAT displacement protein (Drosophila) |
364975 | LCHN | AF136629 | LCHN protein |
742596 | SYTL5 | BX647688 | Synaptotagmin-like 5 |
2346678 | KIAA1324 | AB037745 | Maba1 |
322555 | EMP2 | AK096403 | Epithelial membrane protein 2 |
200862 | CAV1 | NM_001753 | Caveolin 1, caveolae protein, 22kDa |
214006 | |||
246377 | RHOBTB3 | NM_014899 | Rho-related BTB domain containing 3 |
151883 | |||
33386 | |||
122293 | AA704763 | Transcribed locus | |
470059 | FLNA | NM_001456 | Filamin A, alpha (actin binding protein 280) |
41922 | TARS | NM_152295 | Threonyl-tRNA synthetase |
291958 | KLF10 | S81439 | TGFB inducible early growth response |
1461138 | HIST1H4C | CD048335 | Histone 1, H4c |
359040 | IRX1 | AY335938 | Iroquois homeobox protein 1 |
173784 | TMSB4X | BM994376 | Thymosin, beta 4, X-linked |
21892 | IARS | NM_013417 | Isoleucine-tRNA synthetase |
731750 | TAF6L | BC008785 | TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
486591 | SEMA3C | NM_006379 | Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C |
729959 | KIAA1324 | AB037745 | Maba1 |
53243 | ASNS | NM_133436 | Asparagine synthetase |
51583 | SHMT2 | AK055053 | Serine hydroxymethyltransferase 2 (mitochondrial) |
280758 | TMSB4Y | NM_004202 | Thymosin, beta 4, Y-linked |
760230 | AGR2 | BM924878 | Anterior gradient 2 homolog (Xenopus laevis) |
42800 | AI912163 | Transcribed locus | |
45542 | IGFBP5 | NM_000599 | Insulin-like growth factor binding protein 5 |
41195 | GCDH | BC002579 | Glutaryl-Coenzyme A dehydrogenase |
380797 | RBM3 | BX647914 | RNA binding motif (RNP1, RRM) protein 3 |
51865 | CA2 | AK123309 | Carbonic anhydrase II |
668307 | KIAA1199 | AB103330 | KIAA1199 |
214006 | |||
221808 | NAP1L4 | AK095320 | Nucleosome assembly protein 1-like 4 |
26617 | ALCAM | AL833702 | Activated leukocyte cell adhesion molecule |
1926453 | AREG | AK023449 | Amphiregulin (schwannoma-derived growth factor) |
1410444 | AREG | AK023449 | Amphiregulin (schwannoma-derived growth factor) |
1184257 | LMNB1 | BC052951 | Lamin B1 |
726791 | |||
712899 | BMP7 | AK094784 | Bone morphogenetic protein 7 (osteogenic protein 1) |
243549 | MYB | AJ606319 | V-myb myeloblastosis viral oncogene homolog (avian) |
1493527 | ASNS | NM_133436 | Asparagine synthetase |
814615 | MTHFD2 | BC015062 | Methylene tetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase |
547247 | STC1 | NM_003155 | Stanniocalcin 1 |
486591 | SEMA3C | NM_006379 | Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C |
52933 | SLC39A6 | NM_012319 | Solute carrier family 39 (zinc transporter), member 6 |
755474 | IARS | NM_013417 | Isoleucine-tRNA synthetase |
Time up-regulated genes
IMAGE Clone ID | Gene Symbol | Genbank | Description |
---|---|---|---|
207986 | MCRS1 | AK123187 | Microspherule protein 1 |
300041 | NME1 | BM809638 | Non-metastatic cells 1, protein (NM23A) expressed in |
120599 | BCAS3 | BX648103 | Breast carcinoma amplified sequence 3 |
37443 | BAIAP2 | AK098403 | BAI1-associated protein 2 |
235070 | FLJ20619 | AL049431 | Hypothetical protein FLJ20619 |
128041 | WDR40A | NM_015397 | WD repeat domain 40A |
823688 | MAN1A1 | AK025599 | Mannosidase, alpha, class 1A, member 1 |
48518 | ABCA5 | NM_018672 | ATP-binding cassette, sub-family A (ABC1), member 5 |
281240 | SYN2 | NM_003178 | Synapsin II |
2303100 | OLFM3 | NM_058170 | |
156159 | HDAC6 | AL137696 | Histone deacetylase 6 |
263087 | CRY1 | AK125915 | Cryptochrome 1 (photolyase-like) |
1838718 | LOC132671 | BC025396 | LOC132671 |
124286 | RASA2 | CR749587 | MRNA; cDNA DKFZp686C10224 (from clone DKFZp686C10224) |
307307 | TSK | AK126536 | Hypothetical protein, estradiol-induced |
730393 | FTMT | NM_177478 | Ferritin mitochondrial |
201064 | USP34 | AB011142 | Ubiquitin specific protease 34 |
42648 | TKT | BX649193 | Transketolase (Wernicke-Korsakoff syndrome) |
926361 | C1ORF35 | AK126087 | Chromosome 1 open reading frame 35 |
51965 | CFL2 | NM_138638 | Cofilin 2 (muscle) |
376772 | RPS27L | BC047648 | Ribosomal protein S27-like |
125278 | CLDN4 | AK126462 | Claudin 4 |
239754 | SLC7A5 | AF104032 | Solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 |
324593 | MGC16291 | NM_032770 | Hypothetical protein MGC16291 |
294611 | PIK3C2G | AJ000008 | Phosphoinositide-3-kinase, class 2, gamma polypeptide |
148297 | FBXO22 | NM_147188 | F-box protein 22 |
122228 | C20ORF19 | BX648266 | Chromosome 20 open reading frame 19 |
268878 | CYP1B1 | NM_000104 | Cytochrome P450, family 1, subfamily B, polypeptide 1 |
297832 | |||
32510 | BTG2 | NM_006763 | BTG family, member 2 |
233273 | STOM | NM_004099 | Stomatin |
731081 | NALP4 | AF479747 | NACHT, leucine rich repeat and PYD containing 4 |
323511 | C7ORF36 | BX648555 | Chromosome 7 open reading frame 36 |
273392 | PIGF | BM558246 | Phosphatidylinositol glycan, class F |
150728 | TRIM16 | BX537711 | Tripartite motif-containing 16 |
137201 | |||
111753 | SIAT4A | BX537506 | Sialyltransferase 4A (beta-galactoside alpha-2,3-sialyltransferase) |
300595 | BAMBI | CR606572 | BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) |
381786 | MAK | NM_005906 | Male germ cell-associated kinase |
760246 | BLOC1S2 | NM_001001342 | Biogenesis of lysosome-related organelles complex-1, subunit 2 |
35516 | CCNG1 | NM_004060 | Cyclin G1 |
166273 | CDKN1A | NM_078467 | Cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
263446 | IDH1 | AF020038 | Isocitrate dehydrogenase 1 (NADP+), soluble |
144000 | BZW1 | AL833518 | Basic leucine zipper and W2 domains 1 |
205819 | CPM | NM_001874 | Carboxypeptidase M |
324356 | NQO1 | NM_000903 | NAD(P)H dehydrogenase, quinone 1 |
140997 | GDF15 | BQ883534 | Growth differentiation factor 15 |
283648 | BM725828 | Transcribed locus | |
856454 | SLC3A2 | AK025584 | Solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 |
813387 | NQO1 | NM_000903 | NAD(P)H dehydrogenase, quinone 1 |
789376 | TXNRD1 | NM_003330 | Thioredoxin reductase 1 |
2569476 | BAX | BF983096 | BCL2-associated X protein |
41452 | SAT | BF680536 | Spermidine/spermine N1-acetyltransferase |
753447 | DDB2 | BC050455 | Damage-specific DNA binding protein 2, 48kDa |
80631 | |||
547058 | CCNG1 | NM_004060 | Cyclin G1 |
897673 | PGD | NM_002631 | Phosphogluconate dehydrogenase |
768443 | MGST1 | AK123482 | Microsomal glutathione S-transferase 1 |
42739 | PTP4A1 | CR749458 | Protein tyrosine phosphatase type IVA, member 1 |