Microarray Publications Database
Supplementary Data Table 2
Genes identified in HEPG2 cells by 2-way ANOVA as being significantly (p<0.05) affected by BaP concentration and exposure time.
Concentration down-regulated genes
IMAGE Clone ID | Gene Symbol | Genbank | Description |
---|---|---|---|
1643852 | SPAG16 | CR749477 | PF20 |
154996 | AI732317 | Transcribed locus | |
136075 | FLJ35036 | XM_172341 | Hypothetical protein FLJ35036 |
110931 | PCNA | BE896331 | Proliferating cell nuclear antigen |
376772 | RPS27L | BC047648 | Ribosomal protein S27-like |
324356 | NQO1 | NM_000903 | NAD(P)H dehydrogenase, quinone 1 |
205866 | AKR1C3 | BQ939577 | Aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) |
152435 | TUBB6 | AK092677 | Tubulin beta MGC4083 |
809523 | APOC2 | BG568052 | Apolipoprotein C-II |
897491 | JAG1 | AF003837 | Jagged 1 (Alagille syndrome) |
263087 | CRY1 | AK125915 | Cryptochrome 1 (photolyase-like) |
243488 | K-ALPHA-1 | AK094717 | Tubulin, alpha, ubiquitous |
46723 | NELL1 | BX538019 | NEL-like 1 (chicken) |
234314 | APOC1 | AJ249921 | Apolipoprotein C-I |
323511 | C7ORF36 | BX648555 | Chromosome 7 open reading frame 36 |
139835 | UGDH | AF061016 | UDP-glucose dehydrogenase |
196784 | AL359654 | Similar to Kruppel-like factor 7 (ubiquitous); ubiquitous Kruppel-like transcription factor | |
1473211 | HIST1H2BN | CA310244 | Histone 1, H2bn |
1868295 | GEM | NM_005261 | GTP binding protein overexpressed in skeletal muscle |
259649 | IER3 | BM994398 | Immediate early response 3 |
760246 | BLOC1S2 | NM_001001342 | Biogenesis of lysosome-related organelles complex-1, subunit 2 |
381786 | MAK | NM_005906 | Male germ cell-associated kinase |
205819 | CPM | NM_001874 | Carboxypeptidase M |
233273 | STOM | NM_004099 | Stomatin |
140997 | GDF15 | BQ883534 | Growth differentiation factor 15 |
796147 | PLEKHH1 | AB033026 | Pleckstrin homology domain containing, family H (with MyTH4 domain) member 1 |
526657 | TCEB3 | AK096079 | Transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A) |
878564 | GPC3 | CR627361 | Glypican 3 |
240518 | SERPINA6 | BC036818 | Serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 |
34795 | DAZAP2 | AK125855 | DAZ associated protein 2 |
79502 | |||
123474 | SCD | NM_005063 | Stearoyl-CoA desaturase (delta-9-desaturase) |
34888 | RELN | U79716 | Reelin |
840944 | EGR1 | NM_001964 | Early growth response 1 |
841620 | DPYSL2 | AL833091 | Dihydropyrimidinase-like 2 |
Concentration up-regulated genes
IMAGE Clone ID | Gene Symbol | Genbank | Description |
---|---|---|---|
21741 | CACNA1I | NM_021096 | Calcium channel, voltage-dependent, alpha 1I subunit |
234212 | APOH | BG564677 | Apolipoprotein H (beta-2-glycoprotein I) |
51783 | MUM1 | NM_032853 | Melanoma associated antigen (mutated) 1 |
302556 | HUMMLC2B | BF575830 | Myosin light chain 2 |
22376 | BX338520 | BX338520 Homo sapiens PLACENTA COT 25-NORMALIZED Homo sapiens cDNA clone CS0DI060YN11 3-PRIME, mRNA sequence. | |
233143 | FGG | CR620626 | Fibrinogen, gamma polypeptide |
166616 | FAIM2 | NM_012306 | Fas apoptotic inhibitory molecule 2 |
241423 | MAFG | NM_002359 | V-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian) |
1473211 | HIST1H2BN | CA310244 | Histone 1, H2bn |
2307464 | ALS2CR19 | BX647481 | Amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 19 |
166273 | CDKN1A | NM_078467 | Cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
210455 | C1QG | BM713106 | Complement component 1, q subcomponent, gamma polypeptide |
140997 | GDF15 | BQ883534 | Growth differentiation factor 15 |
1473304 | AKR1C3 | BQ939577 | Aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) |
276091 | ITPKB | AJ242780 | Inositol 1,4,5-trisphosphate 3-kinase B |
378461 | |||
784772 | AKAP12 | NM_005100 | A kinase (PRKA) anchor protein (gravin) 12 |
196992 | AKR1C1 | AK095239 | Aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) |
244307 | SERPINE1 | BX649164 | Serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
768443 | MGST1 | AK123482 | Microsomal glutathione S-transferase 1 |
810724 | IER3 | BM994398 | Immediate early response 3 |
214990 | GSN | AK125819 | Gelsolin (amyloidosis, Finnish type) |
Time down-regulated genes
IMAGE Clone ID | Gene Symbol | Genbank | Description |
---|---|---|---|
1412245 | CPA2 | BC007009 | Carboxypeptidase A2 (pancreatic) |
1035248 | KSP37 | NM_031950 | Ksp37 protein |
137535 | TIF1 | NM_015905 | Transcriptional intermediary factor 1 |
210455 | C1QG | BM713106 | Complement component 1, q subcomponent, gamma polypeptide |
233143 | FGG | CR620626 | Fibrinogen, gamma polypeptide |
122906 | MYO1B | NM_012223 | Myosin IB |
267256 | CTGF | NM_001901 | Connective tissue growth factor |
233279 | SCD | NM_005063 | Stearoyl-CoA desaturase (delta-9-desaturase) |
234212 | APOH | BG564677 | Apolipoprotein H (beta-2-glycoprotein I) |
248095 | LOC92497 | AK131330 | Hypothetical protein LOC92497 |
1461138 | HIST1H4C | CD048335 | Histone 1, H4c |
731750 | TAF6L | BC008785 | TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
129467 | HIST1H2BJ | BF983642 | Histone 1, H2bj |
214006 | |||
486195 | THBS1 | NM_003246 | Thrombospondin 1 |
1524557 | HIST1H3E | BG676315 | Histone 1, H3e |
1842170 | HIST1H4B | BX102654 | Histone 1, H4b |
268891 | HIST1H3D | BQ051491 | Histone 1, H3d |
140997 | GDF15 | BQ883534 | Growth differentiation factor 15 |
1473211 | HIST1H2BN | CA310244 | Histone 1, H2bn |
34795 | DAZAP2 | AK125855 | DAZ associated protein 2 |
79502 | |||
204148 | RPS6KA3 | NM_004586 | Ribosomal protein S6 kinase, 90kDa, polypeptide 3 |
34888 | RELN | U79716 | Reelin |
212188 | APOH | BG564677 | Apolipoprotein H (beta-2-glycoprotein I) |
878564 | GPC3 | CR627361 | Glypican 3 |
840944 | EGR1 | NM_001964 | Early growth response 1 |
796147 | PLEKHH1 | AB033026 | Pleckstrin homology domain containing, family H (with MyTH4 domain) member 1 |
123474 | SCD | NM_005063 | Stearoyl-CoA desaturase (delta-9-desaturase) |
898092 | CTGF | NM_001901 | Connective tissue growth factor |
526657 | TCEB3 | AK096079 | Transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A) |
841620 | DPYSL2 | AL833091 | Dihydropyrimidinase-like 2 |
267256 | CTGF | NM_001901 | Connective tissue growth factor |
240518 | SERPINA6 | BC036818 | Serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 |
214006 | |||
840654 | PRH1 | CR598768 | Full-length cDNA clone CS0DE005YD08 of Placenta of Homo sapiens (human) |
Time up-regulated genes
IMAGE Clone ID | Gene Symbol | Genbank | Description |
---|---|---|---|
152435 | TUBB6 | AK092677 | Tubulin beta MGC4083 |
809523 | APOC2 | BG568052 | Apolipoprotein C-II |
46723 | NELL1 | BX538019 | NEL-like 1 (chicken) |
376772 | RPS27L | BC047648 | Ribosomal protein S27-like |
234314 | APOC1 | AJ249921 | Apolipoprotein C-I |
196784 | AL359654 | Similar to Kruppel-like factor 7 (ubiquitous); ubiquitous Kruppel-like transcription factor | |
122906 | MYO1B | NM_012223 | Myosin IB |
173188 | OKL38 | AY258066 | Pregnancy-induced growth inhibitor |
136075 | FLJ35036 | XM_172341 | Hypothetical protein FLJ35036 |
139835 | UGDH | AF061016 | UDP-glucose dehydrogenase |
897491 | JAG1 | AF003837 | Jagged 1 (Alagille syndrome) |
154996 | AI732317 | Transcribed locus | |
259649 | IER3 | BM994398 | Immediate early response 3 |
811740 | ITGA2 | X17033 | Integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
205866 | AKR1C3 | BQ939577 | Aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) |
381786 | MAK | NM_005906 | Male germ cell-associated kinase |
731750 | TAF6L | BC008785 | TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
263087 | CRY1 | AK125915 | Cryptochrome 1(photolyase-like) |
2353276 | CCL20 | BG534134 | Chemokine (C-C motif) ligand 20 |
784772 | AKAP12 | NM_005100 | A kinase (PRKA) anchor protein (gravin) 12 |
129467 | HIST1H2BJ | BF983642 | Histone 1, H2bj |
214006 | |||
324356 | NQO1 | NM_000903 | NAD(P)H dehydrogenase, quinone 1 |
486195 | THBS1 | NM_003246 | Thrombospondin 1 |
1842170 | HIST1H4B | BX102654 | Histone 1, H4b |
25398 | UNC84A | BX640866 | Unc-84 homolog A (C.elegans) |
268891 | HIST1H3D | BQ051491 | Histone 1, H3d |
140997 | GDF15 | BQ883534 | Growth differentiation factor 15 |
1473211 | HIST1H2BN | CA310244 | Histone 1, H2bn |
276091 | ITPKB | AJ242780 | Inositol 1,4,5-trisphosphate 3-kinase B |
668685 | IGFBP1 | CR595377 | Insulin-like growth factor binding protein 1 |
796694 | BIRC5 | BM909357 | Baculoviral IAP repeat-containing 5 (survivin) |
1473304 | AKR1C3 | BQ939577 | Aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) |
810724 | IER3 | BM994398 | Immediate early response 3 |
789376 | TXNRD1 | NM_003330 | Thioredoxin reductase 1 |
768443 | MGST1 | AK123482 | Microsomal glutathione S-transferase 1 |
361639 | GCLM | NM_002061 | Glutamate-cysteine ligase, modifier subunit |
590369 | SERPINE1 | BX649164 | Serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
784772 | AKAP12 | NM_005100 | A kinase (PRKA) anchor protein (gravin) 12 |
789182 | PCNA | BE896331 | Proliferating cell nuclear antigen |
244307 | SERPINE1 | BX649164 | Serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
378461 | |||
214990 | GSN | AK125819 | Gelsolin (amyloidosis, Finnish type) |
196992 | AKR1C1 | AK095239 | Aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) |